Preference Distributions of Primary Motor Cortex Neurons Reflect Control Solutions Optimized for Limb Biomechanics

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Preference Distributions of Primary Motor Cortex Neurons Reflect Control Solutions Optimized for Limb Biomechanics

Neurons in monkey primary motor cortex (M1) tend to be most active for certain directions of hand movement and joint-torque loads applied to the limb. The origin and function of these biases in preference distribution are unclear but may be key to understanding the causal role of M1 in limb control. We demonstrate that these distributions arise naturally in a network model that commands muscle ...

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A prevailing theory in the cortical control of limb movement posits that premotor cortex initiates a high-level motor plan that is transformed by the primary motor cortex (MI) into a low-level motor command to be executed. This theory implies that the premotor cortex is shielded from the motor periphery, and therefore, its activity should not represent the low-level features of movement. Contra...

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ژورنال

عنوان ژورنال: Neuron

سال: 2013

ISSN: 0896-6273

DOI: 10.1016/j.neuron.2012.10.041